Basket (0 Items) - Amount: 0.00$8- Chloroadenosine- 3', 5'- cyclic monophosphate ( 8-Cl-cAMP )
Site-selective PKA agonist
Cat. No.: C 007 CAS No.: [41941-56-4] Bulk available
C10H10ClN5O6P•Na; MW 385.6; λmax 262 nm; ε 17000; soluble sodium salt, purity > 99% HPLC. For metabolites of 8-Cl-cAMP please refer to Cat. No. C 008; for related items or other salt forms please inquire. Site selective cyclic AMP analogue with high selectivity for protein kinase A type I. Induces growth inhibition and differentiation in cultured cancer cell lines and has been tested in several clinical trials already. Detailed technical information and updated reference available on request. Reference: Schwede et al., Pharmacol. Ther., 87, 199 – 226 (2000).
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