0 Items - $0.00
Categories
A to Z

HJC0197

4- Cyclopentyl- 2- (2, 5- dimethylbenzylsulfanyl)- 6- oxo- 1, 6- dihydropyrimidine- 5- carbonitrile ( HJC0197 )
Membrane-permeant inhibitor of Epac 1 and Epac 2
Cat. No.: C 136
    
CAS No.: [1383539-73-8]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 136-05
Unit: 5 µmol / ~1.7 mg
$345.00
According to Chen et al. (2012) HJC0197 is a membrane-permeant inhibitor of Epac 1 and Epac 2. Detailed technical information available. Reference: Chen et al., Bioorg. Med. Chem. Lett., 22, 4038 - 4043 (2012).
Cat. No. C 136
CAS number [1383539-73-8]
Purity > 95% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₉H₂₁N₃OS
Molecular weight [g/mol] 339,5
Target Epac Inhibitor
Absorption max [nm] 304
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14700
  • 1. Rehmann H., Sci. Rep., 3: 3032, 0, 0 - 0 (2013), "Epac-Inhibitors: Facts and Artefacts"
  • 2. Chen H., Tsalkova T., Mei F. C., Hu Y., Cheng X.Zhou J., Bioorg. Med. Chem. Lett., 22, 4038 - 4043 (2012), "5-Cyano-6-Oxo-1,6-Dihydro-Pyrimidines as Potent Antagonists Targeting Exchange Proteins Directly Activated by cAMP"