According to Almahariq et al. (2013) ESI-09 is a membrane-permeant inhibitor of Epac 1 and Epac 2. Detailed technical information available. Reference: Almahariq et al., Mol. Pharmacol., 83, 122 - 128 (2013).
| Cat. No. | B 133 |
| CAS number | [263707-16-0] |
| Purity | > 95% HPLC |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₆H₁₅ClN₄O₂ |
| Molecular weight [g/mol] | 330.8 |
| Target | Epac Inhibitor |
| Absorption max [nm] | 384 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 25300 |
- 1. Almahariq M., Tsalkova T., Mei F. C., Chen H., Zhou J., Sastry S. K., Schwede F.Cheng X., Mol. Pharmacol., 83, 122 - 128 (2013), "A Novel EPAC Specific Inhibitor Suppresses Pancreatic Cancer Cell Migration and Invasion"
- 2. Rehmann H., Sci. Rep., 3: 3032, 0, 0 - 0 (2013), "Epac-Inhibitors: Facts and Artefacts"
