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Rp-cAMPS

Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-cAMPS ), sodium salt
Membrane permeant and PDE-resistant inhibitor of PKA
Cat. No.: A 002 S
    
CAS No.: [73208-40-9]
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Product Name Price (net) Qty
Cat. No.: A 002-05 S
Unit: 5 µmol / ~1.8 mg
$297.00

Specially purified from adenosine, cAMP and Sp-cAMPS. For other salt forms please inquire. Competitive inhibitor of protein kinase A type I and II (cyclic AMP antagonist). Prefers type II of protein kinase A. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic compared to cAMP. Detailed technical information and updated reference list available on request. Rp-cAMPS is also available in an inexpensive lower purity form (A 002 T Economy Grade) and as bulk ware. Ref.: Gjertsen et al., J. Biol. Chem., 270, 20599 - 20607 (1995).

Cat. No. A 002 S
CAS number [73208-40-9]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₁N₅O₅PS · Na
Molecular weight [g/mol] 367,3
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Target PKA (cAK) Inhibitor
Lipophilicity 1.21
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15200
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