8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-PIP-cAMPS )
C15H20N6O5PS•Na; MW 450.4; λmax 273 nm; ε 15000; sodium salt; purity > 98%. For other salt forms please inquire. Lipophilic site-selective cyclic AMP analogue with extremely high selectivity for site B of protein kinase A type II. Acts synergistically with site A activating analogues for selective activation of type II. Metabolically stable and good membrane permeability. Detailed technical information and updated reference list available. Reference: Øgreid et al., Eur. J. Biochem., 221, 1089 - 1094 (1994).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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