Basket (0 Items) - Amount: 0.00$2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2'-O-MB-cAMPS )
Metabolically activatable Form of the PKA inhibitor Rp-cAMPS
Cat. No.: M 004 CAS No.: [152218-23-0]
C14H17N5O6PS•Na; MW 437.4; λmax 258 nm; ε 15000; sodium salt; purity > 97% HPLC. Lipophilic precursor of Rp-cAMPS (Cat. No. A 002), a competitive inhibitor of protein kinase A. During metabolic activation by esterases the inhibitor and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Rp-cAMPS. Resistant against mammalian phosphodiesterases. Detailed technical information and updated reference available for Rp-cAMPS on request. Reference: Vischer et al., Blood, 91, 118 - 127 (1998).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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