0 Items - $0.00
Categories
A to Z

Alternative structural projections:

Sp-2'-O-MB-cAMPS

2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2'-O-MB-cAMPS ), sodium salt
Metabolically activatable form of the PDE-resistant PKA agonist Sp-cAMPS
Cat. No.: M 005
    
CAS No.: [152218-23-0]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: M 005-05
Unit: 5 µmol / ~2.2 mg
$212.00
For other salt forms please inquire. Sp-2'-O-MB-cAMPS is a lipophilic precursor of Sp-cAMPS (Cat. No. A 003), a PDE-resistant activator of protein kinase A. During metabolic activation by esterases Sp-cAMPS and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Sp-cAMPS. Detailed technical information available. Reference: Hügl et al., J. Biol. Chem., 273, 17771 - 17779 (1998); Ouyang et al., Proc. Natl. Acad. Sci. USA, 105, 11993 - 11997 (2008).
Cat. No. M 005
CAS number [152218-23-0]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₄H₁₇N₅O₆PS · Na
Molecular weight [g/mol] 437,4
Modifications 2'-cAMP
Lipophilicity 2.10
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15200