8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-OH-cAMPS )
C10H11N5O6PS•Na; MW 383.3; λmax 268 nm; ε 11000; sodium salt; purity > 99% HPLC. For other salt forms please inquire. Polar, membrane-impermeant analogue of the protein kinase A activator Sp-cAMPS (Cat. No. A 003), e.g. for the study of extracellular cAMP receptors. If applied by patch clamp techniques, Sp-8-OH-cAMPS should remain trapped inside the cell. Highly resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Detailed technical information available.
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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