C₁₀H₁₁N₅O₅PS•Na; MW 367.3; λ_max 258 nm; ε 15000; sodium salt; purity > 99% HPLC, specially purified: Corresponding Rp- isomer below detection limits. For other salt forms please inquire. Activator of protein kinase A (cyclic AMP agonist). Considerably higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl or 8-Br-cAMP, no metabolic side effects. Membrane permeability comparable to 8-Br-cAMP. Detailed technical information and updated reference list available on request. Reference: Tsien et al.: J. Cell Biol., 117, 57 - 72 (1992). Sp-cAMPS is also available in an inexpensive lower purity form ( A 003 T Economy Grade ) and as bulk ware, as well as with functionalized spacers in positions 2, 6, 8 and 2', and correspondingly immobilized to affinity gels.

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