Basket (0 Items) - Amount: 0.00$8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-Br-2'-O-Me-cAMP )
Epac agonist
Cat. No.: B 022 CAS No.: [612513-13-0] Bulk available
C11H12BrN5O6P.Na; MW 444.1; λmax 264 nm; ε 17000; sodium salt; purity > 98% HPLC. For other salt forms please inquire. Specific activator of the exchange protein activated by cyclic AMP (Epac) or cAMP-GEF, respectively, while protein kinase A is not affected. Suitable for direct comparison with common 8-Br-cAMP (Cat. No. B 007), which activates both, PKA and Epac. Detailed technical information and updated reference list available. References: Christensen et al., J. Biol. Chem., 278, 35394 - 35402 (2003); Traver et al., Mol. Pharmacol., 70, 30 - 40 (2006).
Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
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