Basket (0 Items) - Amount: 0.00$8- Bromo- 2'- O- monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-MB-cAMPS )
Metabolically activatable form of the PKA inhibitor Rp-8-Br-cAMPS
Cat. No.: B 010 CAS No.: [788807-32-9]
C14H16BrN5O6PS•Na; MW 516.2; λmax 264 nm; ε 17000; sodium salt; purity > 97% HPLC. For other salt forms please inquire. Lipophilic precursor of the protein kinase A inhibitor Rp-8-Br-cAMPS (Cat. No. B 001). During metabolic activation by esterases the inhibitor and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Rp-8-Br-cAMPS. Detailed technical information and updated reference list available for Rp-8-Br-cAMPS on request. Reference: Ruiz-Velasco et al., Circ. Res., 82, 557 - 565 (1998).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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