Basket (0 Items) - Amount: 0.00$8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cAMPS )
Lipophilic analog of the cyclic AMP antagonist Rp-cAMPS
Cat. No.: B 001 CAS No.: [129735-00-8] Bulk available
C10H10BrN5O5PS.Na; MW 446.2; λmax 264 nm; ε 17000; sodium salt; purity > 99% HPLC. For other salt forms please inquire. Lipophilic analog of the cyclic AMP antagonist Rp-cAMPS. Prefers type I of protein kinase A. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane-permeant compared to Rp-cAMPS or 8-Br-cAMP. Detailed technical information and updated reference list available on request. References: Gjertsen et al., J. Biol. Chem., 270, 20599 - 20607 (1995), Aandahl et al., FASEB J., 12, 855 - 863 (1998).
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