Basket (0 Items) - Amount: 0.00$8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-Br-cAMPS )
Membrane-permeant and PDE-resistant PKA agonist
Cat. No.: B 002 CAS No.: [127634-20-2] Bulk available
C10H10BrN5O5PS.Na; MW 446.2; λmax 264 nm; ε 17000; sodium salt; purity > 99% HPLC. For other salt forms please inquire. Metabolically resistant activator of protein kinase A (cyclic AMP agonist). No metabolic side effects as observed with dibutyryl-cAMP or 8-Br-cAMP. Significantly more lipophilic and membrane-permeant compared to Sp-cAMPS (Cat. No. A 003). Detailed technical information and updated reference list available on request. References: Schaap et al., J. Biol. Chem., 268, 6323 - 6331 (1993); Sandnes et al., Pharmacol. Toxicol., 79, 15 - 22 (1996).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI.
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