Specially purified: Corresponding Rp-isomer below detection limits. For other salt forms please inquire. Activator of protein kinase A (cyclic AMP agonist). Considerably higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl or 8-Br-cAMP, no metabolic side effects. Membrane permeability comparable to 8-Br-cAMP. Detailed technical information and updated reference list available on request. Reference: Tsien et al.: J. Cell Biol., 117, 57 - 72 (1992).
Cat. No. | A 003 S |
CAS number | [71774-13-5] |
Purity | > 99% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₀H₁₁N₅O₅PS · Na |
Molecular weight [g/mol] | 367.3 |
cAMP modified at the exocyclic oxygen | axial (Sp-) |
Target | PKA (cAK) Activator |
Lipophilicity | 1.31 |
Absorption max [nm] | 259 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15200 |