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DEACM-caged cGMP

(7- Diethylaminocoumarin- 4- yl)methylguanosine- 3', 5'- monophosphate (DEACM-caged cGMP)
Caged cyclic GMP, releasing a fluorescent coumarin upon uncaging
Cat. No.: D 043
CAS No.: [339291-42-8]
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Product Name Price (net) Qty
Cat. No.: D 043-001
Unit: 0.1 µmol / ~63 µg
Axial isomer, for the corresponding isomeric mixture please inquire. DEACM-caged cGMP is an only weakly fluorescent, caged precursor of the second messenger cyclic cGMP, which upon irradiation, releases both cGMP and a strongly fluorescent coumarin analogue. High lipophilicity but still reasonable solubility in aqueous systems. Detailed technical information available. Reference: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
Cat. No. D 043
CAS number [339291-42-8]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₂₄H₂₇N₆O₉P x 3 H₂O
Molecular weight [g/mol] 628,5
Target PKG (cGK) Activator
Absorption max [nm] 403
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 19300