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DEACM-caged cAMP

(7- Diethylaminocoumarin- 4- yl)methyladenosine- 3', 5'- cyclic monophosphate ( DEACM-caged cAMP )

Caged cAMP releasing fluorescent coumarin upon irradiation
Cat. No.: D 042
CAS No.: [339291-37-1]
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Product Name Price (net) Qty
Cat. No.: D 042-001
Unit: 0.1 µmol / ~58 µg

Axial isomer, for the corresponding isomeric mixture please inquire. DEACM-caged cAMP is an only weakly fluorescent, caged precursor of the second messenger cyclic AMP, which upon irradiation, releases both cAMP and a fluorescent coumarin analogue. High lipophilicity but still reasonable solubility in aqueous systems. Detailed technical information available. Reference: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).

Cat. No. D 042
CAS number [339291-37-1]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₂₄H₂₇N₆O₈P x H₂O
Molecular weight [g/mol] 576,5
cAMP modified at the exocyclic oxygen axial (Sp-)
Target PKA (cAK) Activator
Absorption max [nm] 401
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 18600