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c[A(2',5')pG(2',5')p] / 2'2'-cGAMP

Cyclic (adenosine- (2' −> 5')- monophosphate- guanosine- (2' −> 5')- monophosphate) ( c[A(2',5')pG(2',5')p] / 2'2'-cGAMP / 2',5'-2',5'-cGAMP ), sodium salt
Cat. No.: C 210
    
CAS No.: [1465774-27-9]
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Product Name Price (net) Qty
Cat. No.: C 210-005
Unit: 0.5 µmol / ~337 µg
$155.00

c[A(2',5')pG(2',5')p] is a cyclic dinucleotide structurally related to the metazoan second messenger and STING activator c[G(2',5')pA(3',5')p] (2'3'-cGAMP, Cat. No. C 161). Similar to natural c[G(2',5')pA(3',5')p], c[A(2',5')pG(2',5')p] binds the signalling protein STING and subsequently induces type I interferons. Detailed technical information available. References: Gao et al., Cell, 154, 748 - 762 (2013); Zhang et al., Mol. Cell, 51, 226 - 235 (2013).

Cat. No. C 210
CAS number [1465774-27-9]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₂₀H₂₄N₁₀O₁₃P₂ (free acid)
Molecular weight [g/mol] 674.4 (free acid)
Absorption max [nm] 256
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 25050