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Alternative structural projections:

2-AH-cGMP-Agarose

N²- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel ( 2-AH-cGMP-Agarose )
Cyclic GMP immobilized on agarose gel 
Cat. No.: A 056
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 056-06
Unit: 0.6 ml
$248.00
Cat. No.: A 056-25
Unit: 2.5 ml
$774.00
Cat. No.: A 056-60
Unit: 6 ml
$1,559.00
The second messenger cyclic GMP immobilized on agarose by an aminohexyl spacer attached to the 2-amino group of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Detailed technical information available. References: Kim & Park, J. Biochem. Mol. Biol., 36, 299 - 304 (2003); Margarucci et al., Mol. BioSyst., 7, 2311 - 2319 (2011). Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Cat. No. A 056
CAS number [pending]
Storage temperature 4°C / 39°F
Modifications 2-cGMP
  • 1. Donaldson L.Meier S., Methods Mol. Biol., 1016, 155 - 173 (2013), "An Affinity Pull-Down Approach to Identify the Plant Cyclic Nucleotide Interactome"
  • 2. Margarucci L., Roest M., Preisinger C., Bleijerveld O. B., van Holten T. C., Heck A. J. R.Scholten A., Mol. Biosyst., 7, 2311 - 2319 (2011), "Collagen Stimulation of Platelets Induces a Rapid Spatial Response of cAMP and cGMP Signaling Scaffolds"
  • 3. Scholten A., Poh M. K., Vandekerckhove J., van Breukelen B., Vos M. A.Heck A. J. R., J. Proteome Res., 5, 1435 - 1447 (2006), "Analysis of the cGMP/cAMP Interactome Using a Chemical Proteomics Approach in Mammalian Heart Tissue Validates Sphingosine Kinase Type 1-interacting Protein as a Genuine and Highly Abundant AKAP"
  • 4. Kim E.Park J. M., J. Biochem. Mol. Biol., 36, 299 - 304 (2003), "Identification of Novel Target Proteins of Cyclic GMP Signaling Pathways Using Chemical Proteomics"