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Rp-8-OH-cAMPS

8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-OH-cAMPS ), sodium salt
Polar, PDE-resistant analogue of the PKA inhibitor Rp-cAMPS
Cat. No.: H 004
    
CAS No.: [475084-30-1]
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Product Name Price (net) Qty
Cat. No.: H 004-01
Unit: 1 µmol / ~0.4 mg
$193.00
For other salt forms please inquire. Polar, membrane-impermeant analogue of the protein kinase A inhibitor Rp-cAMPS (Cat. No. A 002), e.g. for the study of extracellular cAMP receptors. If applied by patch clamp techniques, Rp-8-OH-cAMPS should remain trapped inside the cell. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Detailed technical information available.
Cat. No. H 004
CAS number [475084-30-1]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₁N₅O₆PS · Na
Molecular weight [g/mol] 383,3
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 8-cAMP
Target PKA (cAK) Inhibitor
Lipophilicity 0.97
Absorption max [nm] 268
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 11000