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8-ADOA-cAMP

8- (8- Amino- 3, 6- dioxaoctylamino)adenosine- 3', 5'- cyclic monophosphate ( 8-ADOA-cAMP )
cyclic AMP functionalized for conjugation with markers and dyes or for immobilization
Cat. No.: A 033
    
CAS No.: [214272-05-6]
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Product Name Price (net) Qty
Cat. No.: A 033-05
Unit: 5 µmol / ~2.4 mg
$119.00
Site selective cAMP analogue with a hydrophilic spacer, suitable as a ligand in affinity chromatography and for modification with fluorophores. Detailed technical information available. Reference: Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006).
Cat. No. A 033
CAS number [214272-05-6]
Purity > 98% HPLC
Salt form Free acid
Storage temperature -20°C / -4°F
Molecular formula C₁₆H₂₆N₇O₈P
Molecular weight [g/mol] 475.4
Modifications 8-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.14
Absorption max [nm] 274
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Hanke S. E., Bertinetti D., Badel A., Schweinsberg S., Genieser H.-G.Herberg F. W., N. Biotechnol., 28, 294 - 301 (2011), "Cyclic Nucleotides as Affinity Tools: Phosphorothioate cAMP Analogues Adress Specific PKA Subproteomes"
  • 2. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
  • 3. Moll D., Prinz A., Gesellchen F., Drewianka S., Zimmermann B.Herberg F. W., J. Neural. Transm., 113, 1015 - 1032 (2006), "Biomolecular Interaction Analysis in Functional Proteomics"
  • 4. Hahnefeld C.Herberg F. W., Abstract of the 13th Protein Kinase Symposium p. 14, 0, 12 - 15 (2002), "cAMP-dependent Protein Kinase: cAMP Analog Screening Using Surface Plasmon Resonance and Fluorescent Methods"