Basket (0 Items) - Amount: 0.00$8- (4- Chlorophenylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphate ( 8-pCPT-PET-cGMP )
Membrane-permeant PKG agonist
Cat. No.: C 045 CAS No.: [pending]
C24H18ClN5O7PS•Na; MW 609.9; λmax 276 nm; ε 40000; sodium salt; purity > 98% HPLC. For other salt forms please inquire. Highly membrane-permeant activator of cyclic GMP-dependent protein kinase, but most probably inhibitor of the retinal type cGMP-gated ion channel, thus suitable for distinction between kinase and ion channel mediated effects. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. More lipophilic and membrane-permeant compared to 8-Br-PET-cGMP (Cat. No. P 003). Detailed technical information available.
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