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m₂²Guo

N², N²- Dimethylguanosine ( m₂²Guo )
Cat. No.: D 016
    
CAS No.: [2140-67-2]
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Product Name Price (net) Qty
Cat. No.: D 016-100
Unit: 100 µmol / ~31 mg
$110.00
Reference for analysis of degenerated RNA. For other structures carrying the N2, N2- dimethylguanine nucleobase please inquire. N2, N2-, 7- Trimethylguanosine is offered as well (Cat. No. T 009). Detailed technical information available. Reference: Topp et al., Nucleosides Nucleotides, 12, 585 - 596 (1993).
Cat. No. D 016
CAS number [2140-67-2]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₂H₁₇N₅O₅
Molecular weight [g/mol] 311,3
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 12250
UV pH value 11
  • 1. Bullinger D., Neubauer H., Fehm T., Laufer S., Gleiter C. H.Kammerer B., BMC Biochemistry, 8, 1 - 14 (2007), "Metabolic Signature of Breast Cancer Cell Line MCF-7: Profiling of Modified Nucleosides via LC-IT MS Coupling"
  • 2. Bahia D., Avino A., Darzynkiewicz E., Eritja R.Bach-Elias M., Nucleosides Nucleotides Nucleic Acids, 25, 909 - 923 (2006), "Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA"
  • 3. Topp H., Groß H., Heller-Schöch G.Schöch G., Nucleosides Nucleotides, 12, 585 - 596 (1993), "Determination of N6-Threoninocarbonyladenosine, N2, N2-Dimethylguanosine, Pseudouridine and Other Ribonucleosides in Human Breast Milk"
  • 4. Reddy R., Ro-Choi T. S., Henning D., Shibata H., Choi Y. C.Busch H., J. Biol. Chem., 247, 7245 - 7250 (1972), "Modified Nucleosides of Nuclear and Nucleolar Low Molecular Weight Ribonucleic Acid"