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8-Br-GTP

8- Bromoguanosine- 5'- O- triphosphate ( 8-Br-GTP ), sodium salt
Cat. No.: B 012
    
CAS No.: [23197-98-0]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: B 012-05
Unit: 5 µmol / ~3 mg
$176.00

For other salt forms or a guaranteed higher purity please inquire. Analogue of GTP with changed syn/anti ratio for receptor mapping studies and starting structure for 8-modified GTP derivatives. Detailed technical information available. References: Kapuler & Reich, Biochemistry, 10, 4050 - 4061 (1971); Uno et al., Biochim. Biophys. Acta, 228, 282 - 288 (1971).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. B 012
CAS number [23197-98-0]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₅BrN₅O₁₄P₃ (free acid)
Molecular weight [g/mol] 602,1 (free acid)
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200
  • 1. Kapuler A. M.Reich E., Biochemistry, 10, 4050 - 4061 (1971), "Some Stereochemical Requirements of Escherichia coli Ribonucleic Acid Polymerase. Interaction with Conformationally Restricted Ribonucleoside 5'-Triphosphates: 8-Bromoguanosine, 8-Ketoguanosine, and 6-Methylcytidine Triphosphates"
  • 2. Uno H., Oyabu S., Otsuka E.Ikehara M., Biochim. Biophys. Acta., 228, 282 - 288 (1971), "The Effect of Guanosine 5'-Triphosphate Analogues on Protein Synthesis"