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8-Br-5'-AMP

8- Bromoadenosine- 5'- O- monophosphate ( 8-Br-5'-AMP ), sodium salt
Precursor for 8-modified 5’-AMP derivatives
Cat. No.: B 066
    
CAS No.: [23567-96-6]
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Product Name Price (net) Qty
Cat. No.: B 066-10
Unit: 10 µmol / ~4.3 mg
$70.00
For other salt forms or higher purity please inquire. Analogue of 5’-AMP with changed syn/anti ratio for receptor mapping studies and as starting structure for 8-modified 5’-AMP derivatives. Detailed technical information available. References: Lascu et al., Biochemistry, 18, 4818 - 4826 (1979); Carr & Thompson, J. Comp. Physiol., 153, 47 - 53 (1983).
Cat. No. B 066
CAS number [23567-96-6]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₃BrN₅O₇P (free acid)
Molecular weight [g/mol] 426,1 (free acid)
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Ke H.Wang H., Curr. Topics Medicinal Chem., 7, 391 - 403 (2007), "Crystal structures of Phosphodiesterases and Implications on Substrate Specifity and Inhibitor Selectivity"
  • 2. Carr W. E. S.Thompson H. W., J. Comp. Physiol., 153, 47 - 53 (1983), "Adenosine 5'-Monophosphate, an Internal Regulatory Agent, is a Potent Chemoattractant for a Marine Shrimp"
  • 3. Lascu I., Kezdi M., Goia I., Jebeleanu G., Barzu O., Pansini A., Papa S.Mantsch H. H., Biochemistry, 18, 4818 - 4826 (1979), "Enzymatic Properties of 8-Bromoadenine Nucleotides"
  • 4. Morange M., Blanco F. G., Vandenbunder B.Buc H., Eur. J. Biochem., 65, 553 - 563 (1976), "AMP Analogs: Their Function in the Activation of Glycogen Phosphorylase B"