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Alternative structural projections:

6-Biotin-17-NAD⁺

β- Nicotinamide- N⁶- (2- (6- (6- [biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide ( 6-Biotin-17-NAD⁺ ), sodium salt
Cat. No.: N 012
    
CAS No.: [pending]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: N 012-001
Unit: 0.1 µmol / ~116 µg
$230.00
For other salt forms or higher purity please inquire.
Biotinylated analogue of β-NAD+, representing a non-radioactive alternative to radio-labelled β-NAD+ for corresponding studies. Detailed technical information available. Reference for a structurally related 6-Biotin-17-NAD+: Zhang & Snyder, Biochemistry, 32, 2228 - 2233 (1993); Bakondi et al., J. Histochem. Cytochem., 50, 91 - 98 (2002); Klebl et al., Arch. Biochem. Biophys., 347, 155 - 162 (1997).
Cat. No. N 012
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -70°C / -94°F
Molecular formula C₄₅H₆₈N₁₂O₁₈P₂S (free acid)
Molecular weight [g/mol] 1159,1 (free acid)
Absorption max [nm] 265
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 22000
  • 1. Bakondi E., Bai P., Szabo E., Hunyadi J., Gergely P., Szabo C.Virag L., J. Histochem. Cytochem., 50, 91 - 98 (2002), "Detection of Poly(ADP-Ribose) Polymerase Activation in Oxidatively Stressed Cells and Tissues Using Biotinylated NAD Substrate"
  • 2. Cheung A.Zhang J., Analytical Biochemistry, 282, 24 - 28 (2000), "A Scintillation Proximity Assay for Poly(ADP-Ribose) Polymerase"
  • 3. Klebl B. M., Göpel S. O.Pette D., Arch. Biochem. Biophys., 347, 155 - 162 (1997), "Specificity and Target Proteins of Arginine-Specific Mono-ADP-Ribosylation in T-Tubules of Rabbit Skeletal Muscle"
  • 4. Zhang J.Snyder S. H., Biochemistry, 21, 2228 - 2233 (1993), "Purification of a Nitric Oxide-Stimulated ADP-Ribosylated Protein Using Biotinylated Beta-Nicotinamide Adenine Dinucleotide"