0 Items - $0.00
Categories
A to Z

6-(1-MeBu)-ATP

N6- (1- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-(1-MeBu)-ATP ), sodium salt

Cat. No.: M 027
    
CAS No.: [252889-13-7]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: M 027-05
Unit: 5 µmol / ~2.9 mg
$303.00

For other salt forms or a guaranteed higher purity please inquire. Analogue useful for specific interaction with modified receptor proteins (chemical genetics approach). The corresponding diphosphate (Cat. No. M 026) is offered as well. Detailed technical information available. References: Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999); Kumar et al., Methods, 32, 389 - 397 (2004).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. M 027
CAS number [252889-13-7]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₅H₂₆N₅O₁₃P₃ (free acid)
Molecular weight [g/mol] 577,3 (free acid)
Absorption max [nm] 268
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Kumar N. V., Eblen S. T.Weber M. J., Methods, 32, 389 - 397 (2004), "Identifying Specific Kinase Substrates through Engineered Kinases and ATP Analogs"
  • 2. Eblen S. T., Kumar N. V., Shah K., Henderson M. J., Watts C. K. W., Shokat K. M.Weber M. J., J. Biol. Chem., 278, 14926 - 14935 (2003), "Identification of Novel ERK2 Substrates through Use of an Engineered Kinase and ATP Analogs"
  • 3. Habelhah H., Shah K., Huang L., Burlingame A. L., Shokat K. M.Ronai Z., J. Biol. Chem., 276, 18090 - 18095 (2001), "Identification of New JNK Substrate Using ATP Pocket Mutant JNK and a Corresponding ATP Analogue"
  • 4. Gillespie P. G., Gillespie S. K. H., Mercer J. A., Shah K.Shokat K. M., J. Biol. Chem., 274, 31373 - 31381 (1999), "Engineering of the Myosin-Iß Nucleotide-binding Pocket to Create Selective Sensitivity to N6-modified ADP Analogs"
  • 5. Moffat L. D., Brown S. B. A., Grassie M. E., Ulke-Lemée A., Williamson L. M., Walsh M. P.MacDonald J. A., J.Biol.Chem., 286, 36978 - 36991 (0), "Chemical Genetics of Zipper-interacting Protein Kinase Reveal Myosin Light Chain as a Bona Fide Substrate in Permeabilized Arterial Smooth Muscle"