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Alternative structural projections:

1-NH₂-cGMP

1- Aminoguanosine- 3', 5'- monophosphate (1-NH₂-cGMP), sodium salt
Site-selective PKG agonist
Cat. No.: A 041
    
CAS No.: [78033-42-8]
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Product Name Price (net) Qty
Cat. No.: A 041-05
Unit: 5 µmol / ~1.9 mg
$127.00
For other salt forms, or metabolites please inquire. Site-selective cyclic GMP analogue prefering site A of cGK, suitable for synergism studies. Reference: Corbin et al., J. Biol. Chem., 261, 1208 - 1214 (1986).
Cat. No. A 041
CAS number [78033-42-8]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₂N₆O₇P · Na
Molecular weight [g/mol] 382,2
Modifications 1-cGMP
Target PKG (cGK) Activator
Lipophilicity 0.72
Absorption max [nm] 253
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13500(est.)
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  • 7. Corbin J. D., Oegreid D., Miller J. P., Suva R. H., Jastorff B.Doeskeland S. O., J. Biol. Chem., 261, 1208 - 1214 (1986), "Studies of cGMP Analog Specificity and Function of the Two Intrasubunit Binding Sites of cGMP-dependent Protein Kinase"
  • 8. Miller J. P., Uno H., Christensen L. F., Robins R. K.Meyer R. B., Biochem. Pharmacol., 30, 509 - 515 (1981), "Effect of Modification of the 1-, 2-, and 6-Positions of 9-β-D-Ribofuranosylpurine Cyclic 3',5'- Phosphate on the Cyclic Nucleotide Specificity of Adenosine Cyclic 3',5'- Phosphate and Guanosine Cyclic 3',5'- Phosphate-dependent Protein Kinases"