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Sp-UTP-α-S

Uridine- 5'- O- (1-thiotriphosphate), Sp-isomer ( Sp-UTP-α-S ), sodium salt
Cat. No.: U 003
    
CAS No.: [71214-29-4]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: U 003-05
Unit: 5 µmol / ~2.5 mg
$288.00

For other salt forms or a guaranteed higher purity please inquire.
Useful for modulation of UTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to UTP. Accepted by RNA polymerases. Detailed technical information available. Reference: Armstrong et al., Biochemistry, 18, 4120 - 4123 (1979).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. U 003
CAS number [71214-29-4]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₉H₁₅N₂O₁₄P₃S (free acid)
Molecular weight [g/mol] 500.2 (free acid)
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10000
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  • 9. Buzayan J. M., van Tol H., Feldstein P. A.Bruening G., Nucl. Acids Res., 18, 4447 - 4451 (1990), "Identification of a Non-junction Phosphodiester That Influences an Autolytic Processing Reaction of RNA"
  • 10. Frey P. A., Tetrahedron, 38, 1541 - 1567 (1982), "Stereochemistry of Enzymatic Reactions of Phosphates"
  • 11. Eckstein F., Accounts of Chemical Research, 12, 204 - 210 (1979), "Phosphorothioate analogues of nucleotides"
  • 12. Armstrong R. A., Yee D.Eckstein F., Biochemistry, 18, 4120 - 4123 (1979), "Mechanistic Studies on Deoxyribonucleic Acid Dependent Ribonucleic Acid Polymerase from Escherichia coli Using Phosphorothioate Analogues. 2. The Elongation Reaction"
  • 13. Sheu K.-F. R., Richard J. P.Frey P. A., Biochemistry, 18, 5548 - 5556 (1979), "Stereochemical Courses of Nucleotidyltransferase and Phosphotransferase Action. Uridine Diphosphate Glucose Pyrophosphorylase, Galactose-1-phosphate Uridylyltransferase, Adenylate Kinase, and Nucleoside Diphosphate Kinase"
  • 14. Sheu K.-F. R.Frey P. A., J. Biol. Chem., 253, 3378 - 3380 (1978), "UDP-glucose Pyrophosphorylase"
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