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Alternative structural projections:


8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer ( Sp-8-Br-cGMPS ), sodium salt
PDE-resistant analogue of 8-Br-cGMP
Cat. No.: B 006
CAS No.: [153660-03-8]
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Product Name Price (net) Qty
Cat. No.: B 006-10
Unit: 10 µmol / ~4.6 mg
For other salt forms please inquire. Unspecific activator of both protein kinase G I α and protein kinase A. Resistant against cyclic nucleotide phosphodiesterases. Much more lipophilic and membrane-permeant compared to cyclic GMP or Sp-cGMPS ( Cat. No. G 017). Detailed technical information and updated reference list available on request. Reference: Flaadt et al., J. Cell Sci., 105, 255 - 261 (1993).
Cat. No. B 006
CAS number [153660-03-8]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀BrN₅O₆PS · Na
Molecular weight [g/mol] 462,2
Modifications 8-cGMP
Target PKG (cGK) Activator
Lipophilicity 1.45
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200