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Alternative structural projections:


N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose ( Sp-6-AE-cAMPS-Agarose )

PDE-resistant Sp-cAMPS immobilized on agarose
Cat. No.: A 109
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 109-06
Unit: 0.6 ml
Cat. No.: A 109-25
Unit: 2.5 ml
Cat. No.: A 109-60
Unit: 6 ml

The protein kinase A activator Sp-cAMPS (Cat. No., A 003) immobilized on agarose by an aminoethyl spacer attached to position 6 of the ligand. Free Sp-cAMPS is only very slowly metabolized by corresponding phosphodiesterases and thus represents an extraordinary stable ligand. In addition, its reduced binding affinity towards protein kinase A compared to cAMP results in milder desorption conditions during affinity chromatography. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is offered with a longer spacer (Sp-6-AH-cAMPS-Agarose, Cat. No. A 108, p. 72) as well. Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.


Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).

Cat. No. A 109
CAS number [pending]
Appearance Suspension in 30 mM Na₂HPO₄ buffer (pH 7)
Storage temperature 4°C / 39°F
cAMP modified at the exocyclic oxygen axial (Sp-)
Modifications 6-cAMP