For other salt forms please inquire. Potent site-selective activator of cAMP- dependent protein kinases especially suitable for intact cells showing preference for site B of type II isozyme. Completely stable against mammalian PDE types I & III and only extremely slowly hydrolized by cPDE type II. Surpasses the widely used but problematic dibutyryl cAMP or 8-CPT-cAMP in terms of metabolic stability, membrane permeability and potency. The corresponding Rp- isomer is available as well (Cat. No. D 013
). Detailed technical information and updated reference list available. References: Sandberg et al., Biochemistry
, 521 - 527 (1991); Maronde et al., J. Pineal Res
, 170 - 182 (1999); Poppe et al., Nature Methods
, 277 - 278 (2008).