For other salt forms please inquire. Sulfur-modified analogue of the bacterial second messenger c-diAMP (Cat. No. C 088) with increased metabolic stability. Rp,Rp-c-diAMPSS can be useful in studies on ligand-receptor interactions and was reported to enhance the anti-tumor activity of therapeutic vaccines. Detailed technical information available. Reference: Leong et al., J. Immunother. Cancer, 1(Suppl. 1): O20 (2013).
| Cat. No. | C 118 |
| CAS number | [1613726-45-6] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₂₀H₂₄N₁₀O₁₀P₂S₂ (free acid) |
| Molecular weight [g/mol] | 690.6 (free acid) |
| Absorption max [nm] | 259 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 27000 |
- 1. Leong M., Kanne D., Glickman L., Lemmens E., Lauer P., Metchette K., Burdette D., Diner E., Fu J., Soares K., Brockstedt D., Portnoy D. A., Vance R. E., Kim Y., Jaffee E., Pardoll D.Dubensky T., J. Immunother. Cancer (Suppl 1):O20, 1, 0 - 0 (2013), "Modified STING-activating Cyclic Dinucleotide Derivatives Significantly Enhance the Anti-Tumor Activity of Therapeutic Vaccines"
