For other salt forms or a guaranteed higher purity please inquire. Useful for modulation of dCTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dCTP. Not accepted by DNA polymerases. Detailed technical information available. Reference: Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988).
Vial containing 500 µl of 10 mM aqueous solution of pH 7.6
| Cat. No. | D 046 |
| CAS number | [80951-76-4] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | 10 mM aqueous solution of pH 7.6 |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₉H₁₆N₃O₁₂P₃S (free acid) |
| Molecular weight [g/mol] | 483.2 (free acid) |
| Absorption max [nm] | 271 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 9000 |
- 1. Ryder S. P.Strobel S. A., Methods Enzymol., 18, 38 - 50 (1999), "Nucleotide Analog Interference Mapping"
- 2. Abbotts J., SenGupta D. N., Zon G.Wilson S. H., J. Biol. Chem., 263, 15094 - 15103 (1988), "Studies on the Mechanism of Escherichia coli DNA Polymerase I Large Fragment"
- 3. Goody R. S.Isakov M., Tetrahedron Lett., 27, 3599 - 3602 (1986), "Simple Synthesis and Separation of the Diastereomers of alpha-Thio Analogs of Ribo- and Deoxyribo-di- and Triphosphates"
- 4. Goody R., Isakov M.Labeit S., Ger. Offen. DE 3374, 546, 0 - 0 (1985), "DNA Sequencing Involving Alpha-thiodeoxyribonucleotide triphosphate-labeled DNA and Exonuclease Digestion, Synthesis of Alpha-thionucleotide triphosphates and Resolution of the Resulting Diastereomeric Mixture"
