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Alternative structural projections:


8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cGMPS ), sodium salt
PDE-resistant inhibitor of protein kinase G I α and I ß
Cat. No.: B 005
CAS No.: [150418-07-8]
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Product Name Price (net) Qty
Cat. No.: B 005-05
Unit: 5 µmol / ~2.3 mg

For other salt forms please inquire. Inhibitor of protein kinase G I α and I β. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane-permeant compared to cyclic GMP or Rp-cGMPS. Detailed technical information and updated reference list available on request. Reference: Zhuo et al., Nature 368, 635 - 639 (1994).

Cat. No. B 005
CAS number [150418-07-8]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀BrN₅O₆PS · Na
Molecular weight [g/mol] 462,2
Modifications 8-cGMP
Target PKG (cGK) Inhibitor
Lipophilicity 1.29
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200