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Alternative structural projections:


8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel ( Rp-8-AEA-cAMPS-Agarose )
Immobilized cAMP Antagonist
Cat. No.: A 007
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 007-06
Unit: 0.6 ml
Cat. No.: A 007-25
Unit: 2.5 ml
Cat. No.: A 007-60
Unit: 6 ml
The metabolically stable protein kinase A inhibitor Rp-cAMPS (Cat. No. A 002) immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. Free Rp-cAMPS binds to the protein kinase A holoenzyme, but prevents dissociation to free catalytic and regulatory subunits. In addition, it is not hydrolized by mammalian phosphodiesterases. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. This ligand is offered with a longer spacer (Rp-8-AHA-cAMPS-Agarose, Cat. No. A 012) as well. Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Cat. No. A 007
CAS number [pending]
Storage temperature 4°C / 39°F
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 8-cAMP