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Alternative structural projections:


8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-AEA-cAMPS )
The PDE-resistant PKA inhibitor Rp-cAMPS, functionalized for immobilization or conjugation with markers and dyes
Cat. No.: A 180
CAS No.: [221904-78-5]
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Cat. No.: A 180-05
Unit: 5 µmol / ~2 mg

Phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins and suitable for modification with fluorophores and other markers. Detailed technical information available. This ligand is also available with a longer spacer (Rp-8-AHA-cAMPS, Cat. No. A 085), and immobilized on agarose gel (Rp-8-AEA-cAMPS, Cat. No. A 007). Reference: Bertinetti et al., BMC Chem. Biol., 9: 3 (2009).

Cat. No. A 180
CAS number [221904-78-5]
Purity > 98% HPLC
Salt form Free acid
Appearance Solid
Storage temperature -20°C / -4°F
Molecular formula C₁₂H₁₈N₇O₅PS
Molecular weight [g/mol] 403.4
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 8-cAMP
Target PKA (cAK) Inhibitor
Lipophilicity 0.69
Absorption max [nm] 273
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
UV pH value 7
Solvent for UV data Water