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Alternative structural projections:

Rp-2'-AHC-cGMPS-Agarose

2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel ( Rp-2'-AHC-cGMPS-Agarose )
PDE-resistant Rp-cGMPS immobilized on agarose gel
Cat. No.: A 051
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 051-06
Unit: 0.6 ml
$252.00
Cat. No.: A 051-25
Unit: 2.5 ml
$789.00
Cat. No.: A 051-60
Unit: 6 ml
$1,535.00

The PDE-resistant PKG inhibitor Rp-cGMPS (Cat. No. G 016) immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-ribose hydroxyl group such as some phosphodiesterases. This type of gel is also offered with normal cGMP (2'-AHC-cGMP-Agarose, Cat. No. A 059). Detailed technical information available. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.

 

Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7). 

Cat. No. A 051
CAS number [pending]
Appearance Suspension in 30 mM Na₂HPO₄ buffer (pH 7)
Storage temperature 4°C / 39°F
Modifications 2'-cGMP
  • 1. Corrie J. E. T., Pizza C., Makwana J.King R. W., Prot. Express. Purif., 3, 417 - 420 (1992), "Preparation and Properties of an Affinity Support for Purification of Cyclic AMP Receptor Protein from Escherichia coli"