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pppApA

5'- Triphosphoadenylyl- (3' −> 5')- adenosine ( pppApA ), sodium salt

Cat. No.: T 069
    
CAS No.: [17730-98-2]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: T 069-01
Unit: 1 µmol / ~0.8 mg
$212.00

For other salt forms or a guaranteed higher purity please inquire. In pppApA a 5'-ATP unit is connected with a 5'-AMP unit via a 3' → 5' linkage to form a linear dinucleotide. pppApA is considered to be a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP (Cat. No. C 088) and of cyclic oligoadenylates such as c-tetraAMP (Cat. No. C 335). References: Jia et al., Mol. Cell, 75, 944 - 956 (2019); Niewoehner et al., Nature, 548, 543 - 548 (2017); Manikandan et al., PLoS One, 9(1):e86096 (2014).

 

Vial containing 100 µl of 10 mM aqueous solution of pH 7.6

Cat. No. T 069
CAS number [17730-98-2]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₂₀H₂₈N₁₀O₁₉P₄ (free acid)
Molecular weight [g/mol] 836.4 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 27000