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2-MeS-Ado

2- Methylthioadenosine ( 2-MeS-Ado )
Cat. No.: M 033
    
CAS No.: [4105-39-9]
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Product Name Price (net) Qty
Cat. No.: M 033-10
Unit: 10 µmol / ~3.1 mg
$136.00
Inhibitor of human betaine-homocysteine methyltransferase expression and starting material for 2-methylthio nucleotide analogues. Detailed technical information available. References: Zimmerman et al., Biochemistry, 19, 2252 – 2259 (1980); Chattopadhyay et al., Biochem. Biophys. Res. Commun., 343, 203 – 207 (2006); Ou et al., Biochem. J., 401, 87 – 96 (2007).
Cat. No. M 033
CAS number [4105-39-9]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₁H₁₅N₅O₄S
Molecular weight [g/mol] 313.4
Absorption max [nm] 277
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14700
UV pH value 11
  • 1. Ou X., Yang H., Ramani K., Ara A. I., Chen H., Mato J. M.Lu S. C., Biochem. J., 401, 87 - 96 (2007), "Inhibition of Human Betaine-Homocysteine Methyltransferase Expression by S-Adenosylmethionine and Methylthioadenosine"
  • 2. Chattopadhyay M. K., Tabor C. W.Tabor H., Biochem. Biophys. Res. Commun., 343, 203 - 207 (2006), "Methylthioadenosine and Polyamine Biosynthesis in a Saccharomyces Cerevisiae Meu1delta Mutant"
  • 3. Zimmerman T. P., Wolberg G., Duncan G. S.Elion G. B., Biochemistry, 19, 2252 - 2259 (1980), "Adenosine Analogues as Substrates and Inhibitors of S-Adenosylhomocysteine Hydrolase in Intact Lymphocytes"