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Reference for analysis of oxidative stress DNA hydrolysates. The corresponding ribo nucleoside (Cat. No. H 011) and nucleobase (Cat. No. H 007) are available as well. Detailed technical information available. References: Sodum & Fiala, Chem. Res. Toxicol., 14, 438 - 450 (2001); Frelon et al., Free Radical Res., 36, 499 – 508 (2002). This compound is also part of the Ko-Libri compound library (K 001)
Cat. No.
D 050
CAS number
[62471-63-0]
Purity
> 97% HPLC
Storage temperature
-20°C / -4°F
Molecular formula
C₁₀H₁₃N₅O₄
Molecular weight [g/mol]
267.3
Absorption max [nm]
268
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
11000
1. Conners R., Hooley E., Clarke A. R., Thomas S.Brady R. L., J. Mol. Biol., 357, 263 - 274 (2006), "Recognition of Oxidatively Modified Bases within the Biotin-binding Site of Avidin"
2. Frelon S., Douki T.Cadet J., Free Radical Res., 36, 499 - 508 (2002), "Radical Oxidation of the Adenine Moiety of Nucleoside and DNA: 2-Hydroxy-2'-Deoxyadenosine is a Minor Decomposition Product"
3. Sodum R. S.Fiala E. S., Chem. Res. Toxicol., 14, 438 - 450 (2001), "Analysis of Peroxynitrite Reactions with Guanine, Xanthine, and Adenine Nucleosides by High-Pressure Liquid Chromatography with Electrochemical Detection: C8-Nitration and -Oxidation"