This website uses cookies to ensure proper functionality of the shopping cart and checkout progress. By continuing to browse the site you are agreeing to the use of cookies. Click here to learn about cookie settings.
Analogue of potential interest in research on chlorine-stressed DNA. Detailed technical information available. Reference: Masuda et al., J. Biol. Chem., 276, 40486 - 40496 (2001).
Cat. No.
C 025
CAS number
[437715-62-3]
Purity
> 95% HPLC
Storage temperature
-20°C / -4°F
Molecular formula
C₁₀H₁₂ClN₅O₄
Molecular weight [g/mol]
301.7
Absorption max [nm]
258
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
15000
1. Stanley N. R., Pattison D. I.Hawkins C. L., Chem. Res. Toxicol., 23, 1293 - 1302 (2010), "Ability of Hypochlorous Acid and N-Chloramines to Chlorinate DNA and Its Constituents"
2. Badouard C., Masuda M., Nishino H., Cadet J., Favier A.Ravanat J.-L., J. Chromatogr., 827, 26 - 31 (2005), "Detection of Chlorinated DNA and RNA Nucleosides by HPLC Coupled to Tandem Mass Spectrometry as Potential Biomarkers of Inflammation"
3. Suzuki T., Masuda M., Friesen M. D., Fenet B.Oshima H., Nucl. Acids Res., 30, 2555 - 2564 (2002), "Novel Products Generated from 2'-Deoxyguanosine by Hypochlorous Acid or a Myeloperoxidase-H2O2-Cl--System: Identification of Diimino-imidazole and Amino-imidazolone Nucleosides"
4. Suzuki T., Masuda M., Friesen M. D., Fenet B.Ohshima H., Nucl. Acids Res., 30, 2555 - 2564 (2002), "Novel Products Generated from 2'-Deoxyguanosine by Hypochlorous Acid or a Myeloperoxidase-H2O2-Cl System: Identification of Diimino-imidazole and Amino-imidazolone nucleosides"
5. Masuda M., Suzuki T., Friesen M. D., Ravanat J.-L., Cadet J., Pignatelli B., Nishino H.Oshima H., J. Biol. Chem., 276, 40486 - 40496 (2001), "Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils"