Tumor-selective radiosensitizer and of potential interest in research on chlorine-stressed DNA. Detailed technical information available. Reference: Hale et al., Biochem. Pharmacol., 64, 1493 - 1502 (2002).
| Cat. No. | C 081 |
| CAS number | [32387-56-7] |
| Purity | > 95% HPLC |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₉H₁₂ClN₃O₄ |
| Molecular weight [g/mol] | 261.7 |
| Absorption max [nm] | 287 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 7250 |
- 1. Stanley N. R., Pattison D. I.Hawkins C. L., Chem. Res. Toxicol., 23, 1293 - 1302 (2010), "Ability of Hypochlorous Acid and N-Chloramines to Chlorinate DNA and Its Constituents"
- 2. Badouard C., Masuda M., Nishino H., Cadet J., Favier A.Ravanat J.-L., J. Chromatogr., 827, 26 - 31 (2005), "Detection of Chlorinated DNA and RNA Nucleosides by HPLC Coupled to Tandem Mass Spectrometry as Potential Biomarkers of Inflammation"
- 3. Hale J. A. T., Bigelow J. C., Mathews L. A.McCormack J. J., Biochem. Pharmacol., 64, 1493 - 1502 (2002), "Analytical and Pharmacokinetic Studies with 5-Chloro-2'-Deoxycytidine"
- 4. Masuda M., Suzuki T., Friesen M. D., Ravanat J.-L., Cadet J., Pignatelli B., Nishino H.Oshima H., J. Biol. Chem., 276, 40486 - 40496 (2001), "Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils"
