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β-L-dGTP

Guanine- 2'- deoxy- β- L- ribofuranosyl- 5'- O- triphosphate ( β-L-dGTP )

Ribose-modified dGTP analogue
Cat. No.: G 037
    
CAS No.: [198639-09-7]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: G 037-05
Unit: 5 µmol / ~2.5 mg
$330.00

For other salt forms or a guaranteed higher purity please inquire. β-L-dGTP is the mirror image version of naturally occurring β-D-dGTP, where the guanine nucleobase is connected to 2'-deoxy-β-L-ribose. Nucleoside triphosphate precursor for the formation of highly nuclease-resistant L-DNA. L-DNA is used and explored for biological applications like aptamers, molecular beacons and drug nanocarriers. Useful for research into dGTP-dependent receptor proteins. Inhibitor of human telomerase. References: Yamaguchi et al., Nucleosides Nucleotides Nucleic Acids, 20, 1243 - 1246 (2001); Yamaguchi et al., BBRC, 279, 475 - 481 (2000); Gallois-Montbrun et al., Biochem. Pharmacol., 68, 1749 - 1756 (2004).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. G 037
CAS number [198639-09-7]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₆N₅O₁₃P₃ (free acid)
Molecular weight [g/mol] 507.2 (free acid)
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13500
UV pH value 7
Solvent for UV data Water