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Cl-ANT-dATP

3'- O- (5- Chloroanthraniloyl)- 2'- deoxyadenosine- 5'- O- triphosphate ( Cl-ANT-dATP ), sodium salt

Fluorescent dATP analogue
Cat. No.: C 142
    
CAS No.: [pending]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: C 142-01
Unit: 1 µmol / ~0.6 mg
$165.00

For other salt forms or a guaranteed higher purity please inquire. Analogue of 2'-deoxyadenosine-5'-triphosphate with only moderate intrinsic fluorescence (λexc 347 nm, λem ~431 nm). The fluorophore is supposed to have a certain sensitivity for its environment and can change its spectral properties upon binding. Useful for research into dATP-dependent receptor proteins. Potential inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC). References for related ATP analogues: Dove et al., Mol. Pharmacol., 85, 598 - 607 (2014), Pinto et al., Biochem. Phamacol., 82, 358 - 370 (2011), Geduhn et al., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011), Gille et al., J. Biol. Chem., 279, 19955 - 19969 (2004)

 

Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. C 142
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Light-sensitive Yes
Molecular formula C₁₇H₂₀ClN₆O₁₃P₃ (for free acid)
Molecular weight [g/mol] 644.8 (for free acid)
Excitation max [nm] 347
Emission max [nm] 431
Absorption max [nm] 255
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16000
UV pH value 7
Solvent for UV data Water