For other salt forms or a guaranteed higher purity please inquire. Potentiates activity of disease-associated CFTR channel mutants. Detailed technical information available. References: Miki et al., J. Biol. Chem., 285, 19967 - 19975 (2010); Jih et al., J. Physiol., 589, 2719 - 2731 (2011).
Vial containing 500 µl of 10 mM aqueous solution of pH 7.6.
| Cat. No. | D 104 |
| CAS number | [1239610-11-7] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Appearance | 10 mM aqueous solution of pH 7.6 |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₁₈H₂₄N₅O₁₂P₃ (free acid) |
| Molecular weight [g/mol] | 595.3 (free acid) |
| Absorption max [nm] | 269 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 20500 |
- 1. Jih K.-Y., Li M., Hwang T.-C.Bompadre S. G., J. Physiol., 589, 2719 - 2731 (2011), "The Most Common Cystic Fibrosis-associated Mutation Destabilizes the Dimeric State of Nucleotide-binding Domains of CFTR"
- 2. Miki H., Zhou Z., Li M., Hwang T.-C.Bompadre S. G., J. Biol. Chem., 285, 19967 - 19975 (2010), "Potentiation of Disease-associated Cystic Fibrosis Transmembrane Conductance Regulator Mutants by Hydrolyzable ATP Analogs"
