For other salt forms please inquire. Fluorescent analogue of ATP and GTP, respectively, with λexc 408 nm and λem 552 nm, which is supposed to substitute for ATP and GTP in the interaction with various enzymes and proteins. Potential agonist of P2Y purinoceptors and supposed to be inhibitor of soluble guanylate cyclase. It is sensitive to indicators of local environment such as polarity and viscosity, and frequently exhibits a spectral shift and fluorescence enhancement upon binding to a protein. References for the related TNP-GTP: Hiratsuka, T., J. Biol. Chem., 260, 4784 - 4790 (1985), and various TNP-NTPs: Suryanarayana et al., J. Pharmacol. Exp. Ther., 330, 687 - 695 (2009). Reference for 2-MeS-ATP: Ruiz-Stewart et al., Eur. J. Biochem., 269, 2186 - 2193 (2002).
Vial containing 1 ml of 1 mM aqueous solution of pH 8.
Cat. No. | M 124 |
CAS number | [pending] |
Purity | > 95% HPLC |
Salt form | Sodium |
Appearance | 1 mM aqueous solution |
Storage temperature | -70°C / -94°F |
Light-sensitive | Yes |
Molecular formula | C₁₇H₁₈N₇O₂₀P₃S (for free acid) |
Molecular weight [g/mol] | 765.4 (for free acid) |
Excitation max [nm] | 408 |
Emission max [nm] | 552 |
Absorption max [nm] | 408 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 26500 |
UV pH value | 8 |
Solvent for UV data | 0.1 M Tris-HCl |