Analogue of 5'-AMP, useful for covalent photoaffinity labelling of AMP-binding sites. Detailed technical information available. References: Czarnecki et al., Methods Enzymol., 56, 642 - 653 (1979); Seery, Biochim. Biophys. Acta, 612, 195 - 204 (1980); Larsen & Preiss, Biochemistry, 25, 4371 - 4376 (1986); Patil & Datta, Eur. J. Biochem., 177, 569 - 574 (1988).
| Cat. No. | A 179 |
| CAS number | [60731-47-7] |
| Purity | > 97% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Light-sensitive | True |
| Molecular formula | C₁₀H₁₃N₈O₇P (free acid) |
| Molecular weight [g/mol] | 388.2 (free acid) |
| Absorption max [nm] | 281 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 13000 |
| UV pH value | 6 |
- 1. Deng P. S. K., Zhao S.-H., Iyanagi T.Chen S., Biochemistry, 30, 6942 - 6948 (1991), "Photodependent Inhibition of Rat Liver NAD(P)H:Quinone Acceptor Oxidoreductase by (A)-2-Azido-NAD+ and (A) -8-Azido-NAD+"
- 2. Patil R. V.Datta P., Eur. J. Biochem., 177, 569 - 574 (1988), "Photoaffinity Labeling of the Allosteric AMP Site of Biodegradative Threonine Dehydratase of Escherichia Coli with 8-Azido-AMP"
- 3. Larsen C. E.Preiss J., Biochemistry, 25, 4371 - 4376 (1986), "Covalent Modification of the Inhibitor Binding Site(s) of Escherichia Coli ADP-Glucose Synthetase: Specific Incorporation of the Photoaffinity Analogue 8-Azidoadenosine 5'-Monophosphate"
- 4. Seery V. L., Biochim. Biophys. Acta, 612, 195 - 204 (1980), "Interaction of Glycogen Phosphorylase with 8-Azidoadenosine 5'-Monophosphate, a Photoaffinity Analog of AMP"
- 5. Czarnecki J., Geahlen R.Haley B. E., Methods Enzymol., 56, 642 - 653 (1979), "Synthesis and Use of Azido Photoaffinity Analogs of Adenine and Guanine Nucleotides"
