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2-Cl-5'-AMP

2- Chloroadenosine- 5'- O- monophosphate ( 2-Cl-5'-AMP ), sodium salt
Cat. No.: C 054
    
CAS No.: [81921-27-9] (disodium salt) / [21466-01-3] (free acid)
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Product Name Price (net) Qty
Cat. No.: C 054-10
Unit: 10 µmol / ~3.8 mg
$156.00

Analogue of 5'-AMP with a reactive chlorine for introduction of modifications in position 2 of the adenine nucleobase. Detailed technical information available. Reference: Gough et al., J. Med. Chem., 12, 494 - 498 (1969).

Cat. No. C 054
CAS number [81921-27-9] (disodium salt) / [21466-01-3] (free acid)
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₃ClN₅O₇P (free acid)
Molecular weight [g/mol] 381.7 (free acid)
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14200
  • 1. Cusack N. J.Hourani S. M. O., Br. J. Pharmacol., 76, 221 - 227 (1982), "Adenosine 5'-Diphosphate Antagonists and Human Platelets: No Evidence that Aggregation and Inhibition of Stimulated Adenylate Cyclase are Mediated by Different Receptors"
  • 2. Gough G., Maguire M. H.Michal F., J. Med. Chem., 12, 494 - 498 (1969), "2-Chloroadenosine 5'-Phosphate and 2-Chloroadenosine 5'-Diphosphate, Pharmacologically Active Nucleotide Analogs"