For other salt forms please inquire. Relatively polar analogue of cyclic GMP which activate neither protein kinase G nor Epac. 2'-O-Me-cGMP can be used as an inactive control in patch clamp applications. Also suitable for receptor mapping studies. The structurally related cAMP-based analogue
2'-O-Me-cAMP is offered as well (Cat. No. M 050). Detailed technical information available. Reference: Strassmaier & Karpen,
J. Med. Chem.,
50, 4186 - 4194 (2007); Matthiesen & Nielsen,
Biochem. J.,
423, 401 - 409 (2009); Jäger et al.,
Br. J. Pharmacol.,
161, 1645 - 1660 (2010).