For other salt forms please inquire. N-2'-dAD⁺ is a 2'-deoxyadenosine version of the coenzyme nicotinamide adenine dinucleotide (β-NAD+). It is considered to be a substrate for type III CD38 in the enzymatic production of the Transient Receptor Potential Melastatin 2 (TRPM2) channel superagonist dADPR (2'-deoxy-ADPR, Cat. No. D 227). Both N-2'-dAD⁺ and dADPR were proved to be present in Jurkat T cells (all data according to Fliegert et al., Nat. Chem. Biol., 13, 1036 - 1044 (2017)). Reference: Alvarez-Gonzalez, R., Mol. Cell. Biochem., 138, 213 - 219 (1994).
|Cat. No.||N 065|
|Purity||> 95% HPLC|
|Storage temperature||-70°C / -94°F|
|Molecular formula||C₂₁H₂₇N₇O₁₃P₂ (free acid)|
|Molecular weight [g/mol]||647.4 (free acid)|
|Absorption max [nm]||260|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||18000|