For other salt forms please inquire. N-2'-dAD⁺ is a 2'-deoxyadenosine version of the coenzyme nicotinamide adenine dinucleotide (β-NAD+). It is considered to be a substrate for type III CD38 in the enzymatic production of the Transient Receptor Potential Melastatin 2 (TRPM2) channel superagonist dADPR (2'-deoxy-ADPR, Cat. No. D 227). Both N-2'-dAD⁺ and dADPR were proved to be present in Jurkat T cells (all data according to Fliegert et al., Nat. Chem. Biol., 13, 1036 - 1044 (2017)). Reference: Alvarez-Gonzalez, R., Mol. Cell. Biochem., 138, 213 - 219 (1994).
| Cat. No. | N 065 |
| CAS number | [1514900-83-4] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -70°C / -94°F |
| Molecular formula | C₂₁H₂₇N₇O₁₃P₂ (free acid) |
| Molecular weight [g/mol] | 647.4 (free acid) |
| Absorption max [nm] | 260 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 18000 |
